2020;16(3):458-462. View abstract. Clin Neurol Neurosurg 2003;105:286-7.. View abstract. Evid Based Complement Alternat Med. Intern Med 2017;56(2):175-9. Madisch A, Holtmann G, Mayr G, et al. 2020;247:112226. Rees, W. D., Rhodes, J., Wright, J. E., Stamford, L. F., and Bennett, A. J Altern Complement Med 2009;15(4):439-443. Learn more about Peony health benefits, uses, side effects, effectiveness, safety, precautions, and warnings. View abstract. Warfarin is used to slow blood clotting. Medicinal herbs: modulation of estrogen action. Peony for Women's Health and Beyond Kinoshita T, Maruyama K, Yamamoto N, Saito I. View abstract. Paeonia lactiflora Pall inhibits bladder cancer growth involving phosphorylation of Chk2 in vitro and in vivo. The treatment of human cancer with agents prepared from bovine cartilage. Zong, P. P., Yan, T. Y., and Gong, M. M. [Clinical and experimental studies of effects of huayu decoction on scavenging free radicals]. 2004;24(12):1084-1086. Int Immunopharmacol. Botanical names: Paeonia lactiflora, Paeonia suffruticosa, Paeonia veitchii How It Works Peony contains a unique glycoside called paeoniflorin. de Klerk GJ, Nieuwenhuis G, Beutler JJ. Wang Y, Ma R. [Effect of an extract of Paeonia lactiflora on the blood coagulative and fibrinolytic enzymes]. Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. Early evidence suggests that taking 45 grams of a specific product containing peony and licorice (Peony-Glycyrrhiza Decoction, PGD) daily for 4 weeks reduces levels of a hormone called prolactin in women with high levels of prolactin, without affecting other hormone levels or mental symptoms. Tsuda T, Sugaya A, Ohguchi H, et al. Natural Fertility Treatment Options: Copesthetic Health Licorice can decrease potassium levels. Xu, L., Jiang, J., and Du, F. Z. Exp Neurol 1997;146:518-25. Biol Pharm Bull 2000;23:199-203.. View abstract. Cinatl J, Morgenstern B, Bauer G, et al. Some research studies have found Angelica Sinensis to be beneficial for its effects on some symptoms of menopause. It combined licorice, dates, peonies, and skullcap, and was traditionally prepared as a tea. 6. O'Connell K, Kinsella J, McMahon C, Holian J, O'Riordan S. Posterior reversible encephalopathy syndrome (PRES) associated with liquorice consumption. Baykul, T., Alanoglu, E. G., and Kocer, G. Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience. WebMD does not provide medical advice, diagnosis or treatment. View abstract. Awad N, Makar G, Burroughs V, Ravi P, Burroughs SR. Licorice-induced apparent mineralocorticoid excess causing persistent hypertension and hypokalemia. Some sources claim that it's contraindicated during pregnancy . and Glycyrrhiza glabra L. extracts in patients with Familial Mediterranean Fever. Intern Med 2007;46:575-8. Qi XG. View abstract. View abstract. Imtiaz, K. E. Sweet root, bitter pill: liquorice-induced hyperaldosteronism. View abstract. Lin, J. C. Mechanism of action of glycyrrhizic acid in inhibition of Epstein-Barr virus replication in vitro. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. This fragrant, perennial plant -- a member of the celery family -- has smooth purplish stems and umbrella-shaped clusters of white flowers and winged fruits in July and August. Bardhan, K. D., Cumberland, D. C., Dixon, R. A., and Holdsworth, C. D. Clinical trial of deglycyrrhizinised liquorice in gastric ulcer. Lower potassium levels can cause those abnormal heart arrhythmias. Sakamoto S, Kudo H, Suzuki S, et al. 83rd Annual Meeting of the Endocrine Society, June 20-23 2001;abstract P1-573. Estrogenic and antiproliferative properties of glabridin from licorice in human breast cancer cells. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. The combination of Licorice and Peony has been used in TCM for centuries and now used extensively in western herbal medicine for ovarian cysts and PCOS. Front Psychiatry 2020;11:605949. 1979;14(5):605-607. Reuter, J., Merfort, I., and Schempp, C. M. Botanicals in dermatology: an evidence-based review. van Beers, E. J., Stam, J., and van den Bergh, W. M. Licorice consumption as a cause of posterior reversible encephalopathy syndrome: a case report. Liang, R. N., Liu, J., and Lu, J. [Severe hypokalemia after holidays return]. Taking licorice along with "water pills" might make potassium levels drop too low. [Paeonia Lactiflora injection in treating chronic cor pulmonale with pulmonary hypertension]. Kase Y, Saitoh K, Ishige A, et al. Not too many side effects of peony tea that we need to worry about. van Rossum, T. G., Vulto, A. G., Hop, W. C., Brouwer, J. T., Niesters, H. G., and Schalm, S. W. Intravenous glycyrrhizin for the treatment of chronic hepatitis C: a double-blind, randomized, placebo-controlled phase I/II trial. View abstract. Armanini D, Bonanni G, Palermo M. Reduction of serum testosterone in men by licorice. Wilson, J. It contains kojic acid, witch hazel, and licorice extracts that reduce melanin production and exfoliate . . Peony-glycyrrhiza decoction for antipsychotic-related hyperprolactinemia in women with schizophrenia: a randomized controlled trial. PCOS; Fertility; 25 - 45; Menopause; 45 - 60; Pregnancy J Peripher.Nerv.Syst. J Am Acad Dermatol 2011;65(4):699-714. Effect of orally administered shao-yao-gan-cao-tang (Shakuyaku-kanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. Comparative study of bioactive constituents in crude and processed Glycyrrhizae radix and their respective metabolic profiles in gastrointestinal tract in vitro by HPLC-DAD and HPLC-ESI/MS analyses. Peony and Licorice - Radiant Wonder Deglycyrrhizinated liquorice in duodenal ulcer. J Ethnopharmacol 2004;94:339-44. . View abstract. N Engl J Med 1990;322:849-50. Antiviral Res 2003;59(1):41-47. ""- . Maeda T, Shinozuka K, Baba K, et al. Endocrinol Jpn 1991;38(2):167-174. Motherwort, Peony, Dong Quai, Lady's Mantle, Licorice, and Rose, Fennel, Alfalfa. Hattori, M., Sakamoto, T., Kobashi, K., and Namba, T. Metabolism of glycyrrhizin by human intestinal flora. View abstract. That's because licorice real black licorice, not the phony licorice-flavored stuff flavored with anise oil . 2001;21(7):501-503. J Assoc Physicians India 1978;26(9):811-814. Phytotherapy Research 1997;11:207-210. van Gelderen, C. E., Bijlsma, J. Feng ZT, Xu J, He GC, Cai SJ, Li J, Mei ZG. View abstract. Hawrelak, J. View abstract. Nutr Res 2012;32(2):85-92. Luper, S. A review of plants used in the treatment of liver disease: part two. Chin J Integr Med 2022. [Clinical study on treatment of mid-advanced crescentic nephritis by qingre huoxue recipe]. Some medications are changed and broken down by the liver. 2007;30(7):1271-7. Mumoli, N. and Cei, M. Licorice-induced hypokalemia. Yu IC, Tsai YF, Fang JT, Yeh MM, Fang JY, Liu CY. Z Kardiol 1991;80(6):389-391. Indian J Med Res 1993;98:69-74. Prudden JF. J Agric Food Chem 6-13-2007;55(12):4691-4697. Low doses of liquorice can induce hypertension encephalopathy. Licorice can decrease potassium levels. The herb licorice may lower warfarin levels and can add to digoxin's effects. Life Sci 1993;53(5):PL63-8. Nihon Jinzo Gakkai Shi 2010;52(1):80-85. Anesth Analg. Lancet 2-10-1979;1(8111):319. Removes excess melanin: Licorice extract brightens the skin in another way, too. Aoki, F., Nakagawa, K., Kitano, M., Ikematsu, H., Nakamura, K., Yokota, S., Tominaga, Y., Arai, N., and Mae, T. Clinical safety of licorice flavonoid oil (LFO) and pharmacokinetics of glabridin in healthy humans. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. 1994;14:207-9, 195. . Patients received either bromocriptine 5 mg daily for 4 weeks followed by 4 weeks of 22.5 grams daily of the peony-licorice decoction (equivalent to 25 mg of glycyrrhetinic acid), or the same drugs in the reverse order. Cancer Lett 12-10-2001;174(1):17-24. Effects of glycyrrhizin on biochemical tests in patients with chronic hepatitis -- double blind trial. Murakami, T. and Uchikawa, T. Effect of glycyrrhizine on hyperkalemia due to hyporeninemic hypoaldosteronism in diabetes mellitus. Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. Petramfar P, Hajari F, Yousefi G, Azadi S, Hamedi A. Efficacy of oral administration of licorice as an adjunct therapy on improving the symptoms of patients with Parkinson's disease, A randomized double blinded clinical trial. 2009;14(1):64-65. Side effects, toxicity, and interactions. Clin Exp Obstet Gynecol 2013;40(1):141-143. Arch Pharm Res 2002;25(3):293-299. typica. Feng Z, Xu J, He G, et al. Gulf J Oncolog 2021;1(37):42-47. Objective: To evaluate the effect of different ratio of peony and licorice and Christina Loosestrife herb decoction on isolated in New Zealand . View abstract. Volatiles with antimicrobial activity from the roots of Greek Paeonia taxa. 2019;18(Suppl1):291-301. Kwon S, Jin C, Cho SY, et al. We describe a patient who suffered life-threatening hypokalemic paralysis caused by consumption of licorice in the form of a tea sweetener superimposed on long . Gao, X., Wang, W., Wei, S., and Li, W. [Review of pharmacological effects of Glycyrrhiza radix and its bioactive compounds]. Zhong Yao Cai 2000;23:557-60. . [Effectiveness of interferon, glycyrrhizin combination therapy in patients with chronic hepatitis C]. Kim YR, Nam SH. View abstract. Int Hepatol Comm 1997;233-238. Harada M, Suzuki M, Ozaki Y. Contact Dermatitis 2021;85(4):454-455. 2017 Sep;31(9):1330-1340. Zhang W, Leonard T, Bath-Hextall F, et al. A., van der Ven, P. F., Martin, M., Sherman, J., and Haley, J. Luchon, L., Meyrier, A., and Paillard, F. [Hypokalemia without arterial hypertension by licorice poisoning]. Suzuki H, Ohta Y, Takino T, and et al. Fitoterapia 2004;75:45-9.. View abstract. 2019;33(1):117-29. View abstract. [RETRACTED]. View abstract. Nephron 2002;90:240. Pathogenetic considerations and presentation of a clinical case]. 2020;50:102401. View abstract. View abstract. Amaryan G, Astvatsatryan V, Gabrielyan E, et al. Results of a double-blind placebo controlled comparative study]. Pak J Med Sci 2022;38(1):271-275. View abstract. Turpie AG, Runcie J, Thomson TJ. Dellow EL, Unwin RJ, Honour JW. Mol Nutr Food Res 2006;50(11):1080-1086. Russo S, Mastropasqua M, Mosetti MA, et al. Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis. View abstract. View abstract. View abstract. The inhibition of phenylhydroquinone-induced oxidative DNA cleavage by constituents of Moutan Cortex and Paeoniae Radix. Werner, S., Brismar, K., and Olsson, S. Hyperprolactinaemia and liquorice. Do White Peony and Licorice Help with Hirsutism Symptoms? Lee, C. H., Park, S. W., Kim, Y. S., Kang, S. S., Kim, J. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Phytother Res 2009;23(2):246-250. Information from this source is evidence-based and objective, and without commercial influence. Loop diuretics can also decrease potassium levels.
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